In alignment with the university's policy and the College of Applied Sciences' commitment to offering distinctive and unique programs to meet the demands of the local job market and contribute to the development and growth of Palestinian society, the college introduced the Applied Chemistry program in the academic year 2010/2011.

Applied biology involves the practical application of biological knowledge to address a wide range of societal challenges, as the principles of life sciences permeate numerous aspects of our daily lives. It plays a pivotal role in enhancing our health and environmental conditions, particularly in the realms of food production and quality improvement, as well as the advancement of technological industries reliant on living organisms.

In the modern era, electronics and their applications have permeated every aspect of life, becoming an indispensable part of our daily interactions with the world around us. Recognizing this, the College of Applied Sciences introduced the Electronics program in the academic year 2002/2003. Its aim was to cultivate a new generation of professionals, well-versed in both theory and practice, who could navigate the ever-evolving landscape of modern electronic technology.

This program was initiated in the academic year 2000/2001 with the goal of contributing to the process of scientific progress, elevating the standard of technical and applied education, and supplying the labor market with distinguished graduates capable of working in various vital life sectors and excelling in teaching. The curriculum encompasses 130 credit hours, comprising both theoretical and practical components conducted in the department's state-of-the-art laboratories.

The College of Applied Sciences at Palestine Polytechnic University is considered one of the distinguished and leading institutions in Palestine. Established in the academic year 1998/1999, it introduced its first program: Applied Mathematics. Mathematics serves as the fundamental cornerstone for all sciences, whether theoretical or applied. For instance, it is integral to engineering, playing a crucial role in developing models, creating drawings, and simulating reality.

Thanks to significant advancements in multimedia and information technology, we now have the capability to store and edit audio, images, and videos in various ways. This has created a demand for professionals who possess specialized skills and can continuously adapt to the ever-evolving field of multimedia and graphics.

In today's interconnected world, characterized by globalization and rapid changes, information has emerged as the most important resource for decision-making. Recent studies have emphasized that computer technology, alongside information, plays a pivotal role in solving increasingly complex administrative problems. As a result, many organization owners now prefer managing their activities through the latest technological advancements and computerized administrative systems.

In today's competitive environment, employers seek individuals who possess the skills to analyze and evaluate complex business problems, along with the ability to make informed decisions. The Accounting Minor Business Economics program is designed to help students excel in the business world by focusing on the interaction between business and the external economic environment. The program caters to students interested in pursuing a career in accounting, as well as those who aim to understand the economy's impact on business decisions.

Due to the growing need for accountants with exceptional accounting knowledge, skills, and innovative abilities in decision-making and leadership, the College of Administrative Sciences and Informatics introduced the accounting program in 2011. This decision was prompted by the rising demand from the Palestinian, Arab, and international job markets.